International video conference “Security Crises in the 21st Century and How to Manage Them” was organized by the Center for Risk Analysis and Crisis Management from Belgrade (CARUK), the Croatian Association for International Studies (HUMS), the Institute for Development and International Relations (IRMO) and the Libertas International University on the October 13 and 14 2020. The conference brought together leading scientists and experts from countries in the region, as well as the UK, to exchange experiences in risk and crisis management, especially in the context of the COVID-19 pandemic, the migrant crisis and many social and economic challenges across Europe and in the countries of the region. The organizers of the videoconference opted for a multidisciplinary approach to contemporary security challenges, aware that a long-term solution must be sought in connecting different academic disciplines, primarily biomedical, technical and political sciences, as well as security studies. Among the security challenges, COVID-19 stood out in particular, a pervasive crisis that shook the foundations of the world political and economic order. The conference was organized with logistical and IT support from the Institute for Standardization of Serbia.